F5 jumbo MTU

We are building new datacenter and making all network switch run on MTU 9216 in short all my switches running on 10G with jumbo frames.

Question:

I am installing F5

Big-IP-LTM 10000

and created vPC trunk and i set max MTU size supported

9198

but does this means all

Virtual server

i am going to create will run on MTU 9198, is this going to create issue for any public users who is going to access my VIP or any internal datacenter web server who is running on

MTU 1500

default?