How to seperate web servers in same IIS

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You can have two different virtual servers and add required DNS records for the given domain against respective virtual server IP.

Lets say, you have created 10.10.10.10 and 10.10.10.11 virtual servers. Then bind DNS entries as given below,

xyz.com will be pointed to 10.10.10.10 and

abc.com will be pointed to 10.10.10.11

Both virtual server's pool will have same node with desired port.

With this, request coming to xyz.com will hit 10.10.10.10 VS and for abc.com , it will hit 10.10.10.11 VS.

Hope it helps!