Question about Route domain

It won't affect. If you verify using tcpdump inside route domain that doesn't work. Need do it from default RD

    https://support.f5.com/kb/en-us/solutions/public/6000/500/sol6546.html

    Running tcpdump in a route domain

    Recommendations

    When using tcpdump to capture traffic in a non-default route domain, F5 recommends that you run the tcpdump command from the default route domain (route domain 0), and specify interface 0.0.
    Note: Specifying interface 0.0 when running tcpdump captures traffic traversing all configured VLANs on the BIG-IP system.

    For example, the following command captures traffic from all VLANs in all route domains when invoked from the default route domain:

    tcpdump -ni 0.0

Limitations

The tcpdump utility does not capture traffic when run from a non-default route domain. For example, if you use the rdsh utility to change the shell to a non-default route domain and run the tcpdump command, no traffic will be captured. To capture traffic, use the following command to change back to the default route domain:
rdsh 0

You can then run the tcpdump -ni 0.0 command to capture all route domain traffic