LTM 11.5 L4 VS and SSL Persistence terminates IE8 Connections

After upgrading to 11.5 (from 10.x), a Website stopped working with IE8 - FireFox 24.1.1 was working well. (actually in most of the cases just one HTTP Request passed in a 'keep-alive' connection).

While troubleshooting I realized, that this issue is caused by the SSL Persistence Profile which was attached to the Virtual Server. The VS is configured as L4 Service (no SSL Termination).

I'm aware, that Version 11.5 does not make use of SSLv3. So I think this is somehow related.

Anybody else who see the same behaviour?