iRule that can forward traffic based on endpoint and http-method

You can try below code

when HTTP_REQUEST {
if { [string tolower [HTTP::host]] equals "api.example.com" } {
HTTP::header replace "Host" "api.newexample.com"
pool api-newexample-com
return
}
switch -glob [string tolower [HTTP::uri]] {
 "/path1/example*" -
 "/path2/example*"
 { 
 pool pool-example
 } 
 "/version2/sport1*"
 {
  if { [HTTP::method] eq "POST"} {
  pool sport_pool
    } else {
   reject
  }
 } default  { 
  return 
    }
   }
 }