Irule based on source IP and URI request

You might be able to do something similar to the following. If it ends up being a long list I would recommend using a data group and using that to limit your lines of code because iRules do have a line limit.

when CLIENT_ACCEPTED {

    set DEFAULT_POOL [LB::server pool]

}

when HTTP_REQUEST {

    set URI [string tolower [HTTP::uri]]

    if { [IP::addr [IP::client_addr] eq 10.10.10.10] } {
        if { $URI eq "/my/uri/path" } {
            pool my_pool_for_this_uri
        } elseif { $URI eq "/my/other/uri/path" }
            pool my_pool_for_other_uri
        else {
            $DEFAULT_POOL
        }
    } else {
        $DEFAULT_POOL
    }

}