any negative impact using HTTP2

ssl traffic is terminated on F5 and now running with http1.1. WAF is enabled. Now application want to use http2 on LB. for http2 ssl renegotation option should be disabled from ssl profile. Disabling ssl renegotation option from client/server ssl profile and using http2 would have any negative impact(device performace and security).

second I am browsing ecommerce site ex- amazon.com over http1.1. TCP and ssl handshake is already completed. Then I decided to purchase few items and clicked on signing in. will it initiate again ssl handshake process for signing in or will it use existing ssl on http1.1 and how it's different on http2