F5 noob here. I have setup a simple smtp pool (I also tried this with a simple http server too) and the virtual server to go along with it. I have it in its own partition. Pool shows green. Virtual server shows green. I can telnet to 25 on the virtual server. However, sending mail results in unexpected EOF. (When I tried this with the http virtual server, it was the same...could telnet to 80 but the page was "ERR_CONNECTION_RESET"). The smtp hosts currently receive mail by themselves, so I know mail will send successfully.