There is a redirect loop of some kind happening.
Possible reasons:
You have SSL terminated on the VS:443 that is sending the traffic unencrypted to the servers on a specific port (say, port 80). Servers are configured to redirect the traffic to the HTTP version of the site which then hits VS:80 which redirects to VS:443 and so on.
Best way to troubleshoot scenarios like this is to use CURL and send a request with -L as the option in order to follow the redirects.
For example, you have a site called "domain.com", try
curl -IL http://domain.com
and check the "Location" header to identify the subsequent redirects in order to understand where the loop occurs and fix it to suit your environment.