I've reviewed the available info here, but it doesn't seem complete. Aside from configuring persistence, does anyone have suggestions for best practices load balancing MS Net.tcp?
As far as I can see, persistence at layer-4 (i.e source address) is probably about all you can do.
Unless you want to write an irule that parses the net.tcp messages and creates persistence records on a per message basis, there isn't really any other approach.
