Short answer, yes, however there is likely a bit more work and reconfiguration that would be required. What you would need, at the very least, is Route Domains. You can ease some of the administration of placing objects into Route Domains by utilizing Administrative Partitions, and the "Default Route Domain" setting within that Administrative Partition.
https://support.f5.com/kb/en-us/products/big-ip_ltm/manuals/product/tmos-routing-administration-11-6-0/8.html
https://support.f5.com/kb/en-us/products/big-ip_ltm/manuals/product/tmos-implementations-11-6-0/28.print.html
https://support.f5.com/kb/en-us/products/big-ip_ltm/manuals/product/tmos-implementations-11-6-0/11.html
Regards,
Eric
Nimbostratus
