upgrade from v9.4.7 to v10.2.1 issue

Hi all, i'm wondering if i can upgrade F5 LTM 1600 from v9.4.7 to v10.2.1 directly? but not from v9.4.7 to v10.1.0 then v10.1.0 to v10.2.1?   another question,i have to install hotfix and 10.2.1 ...