Persistence based on source tcp/udp port

Yes. The idea of Universal Persistence is so that you can write your own logic, if the system-supplied persistence criteria don't meet your needs.

The example on the solution article for universal persistence is extracting the key from a cookie value. In your case, you will be using source port instead of JSESSIONID cookie.

The idea is generally (pseudocode):

 when CLIENT_ACCEPTED:
   persist uie [TCP::client_port]


 when SERVER_CONNECTED:
   persist add uie [TCP::client_port]

Logic is a little simpler since the port is always present. YOu of course need to test this.