Modify URI among other things

Or if you are using the same node address and port for all the entries in the datagroup, you could change leave that out of the datagroup:

original_uri new_uri datagroup

/PaymentResponse1.jsf /CSU/PaymentResponse.jsf

when HTTP_REQUEST {

   set uri [findclass [HTTP::path] uri_class]
   if {$line ne ""}{
      HTTP::uri $uri
      node 10.48.52.58 8080
   }
}

If you're on 9.4.3 or lower you'll want to add a $:: prefix to the datagroup name in the iRule.

Aaron