F5 LTM VRF/ZONES

I am more familiar with route domains. so basically you should create additional route-domains which are essentially similar to Cisco VRF's. You have the option to select strict-isolation which means the route domain routing table is exclusively used and if there is no match on a route it will use the default route within that RD. You should assign a physical interface north/south of the F5 for each particular route domain. basically you can duplicate VIP addressing on the F5. if you need any more pointers with route-domains let me know. If you are running 11.5 code and higher you can also use HA traffic-groups. so each VS within in each route domain should be configured in a specific traffic-group. that will allow that RD/Traffic-group to failover without impacting the other RD's.