Exclude subfolder from loadbalancing

Rickmmcl, you're on the right track I think, but you need to enable or disable a server SSL profile if you're going between HTTP and HTTPS pools. Add a server SSL profile to your VIP and an iRule like this:

when HTTP_REQUEST {
    if { [string tolower [HTTP::path]] starts_with "/path-not-loadbalanced/" } {
        select proper non-loadbalanced pool
        if { [TCP::local_port] equals "443" } {
            pool nlb-https
        } else {
            pool nlb-http
            SSL::disable serverside
        }
    } else {
         select load balanced pool
        if { [TCP::local_port] equals "443" } {
            pool lb-https
        } else {
            pool lb-http
            SSL::disable serverside
        }
    }
}

And you should probably add a OneConnect profile as well.