Causes of performance Issues in VIP

Nearly always misconfiguration, incorrect profiles and bad irules.

Can you see anything interesting when tail -f /var/log/ltm in shell?

You nearly always have to be very creative to make an application perform significantly worse if going through an LTM...

What do you mean by performance issues ? Can you provide an example ?

Also, if the file being downloaded resides on a RedHat (based) server, switch OFF Nagles algorithm in the tcp profile used.

I know this can be more intelligently addressed, but trust me, just switch it off.