Authentication issues for a VIP when login via IE

Hi All,

 

Can some one please let me know if you come across an issues below

 

we have configured a VIP on f5 LTM and users are seeing Authentication issues and seeing 401 error when they log in to the site Via IE but Chrome works fine

 

Same url if they access on server via IE it works fine.

 

let me know if this is an issue due to some config setting on F5 VIP ?