Rewriting the host and port in the request and response to the server

no need to change the port if it is the default port for backend pool members but if not you can create a new pool with this port and configure LTM policy with condition that request URL to map  traffic to new pool and rewreite the URI. its way easire to use LTM policy.

in response i this that it rewrite the URI in case of redirect traffic only but am not sure.