Is it possible in ASM to block upload microsoft office files that has macro in it ?
AFAIK this should be done in ICAP server or local AntiVirus in the website server , not in ASM. Can you please correct if I'm wrong
ASM can be used to disallow file upload only for binary executable content, in your case you have to integrate the ASM with Antivirus using ICAP to allow an advanced inspection.
Additional review next link to clarify other options with ASM :
Hope it´s works.