No problem.
It depends on how which platform you have, the size of your configuration, if you have generally high the CPU usage or not. Most of the heavy lifting is done on the BigIP-Report server.
At my work place the report is used by the organization to troubleshoot stuff and to know status of objects so we run it as often as we possibly can. The whole batch takes ~20 minutes to finish so the Scheduled Task has been set to run every 30 minutes in case of slow network/BigIP-report server.
You can test yourself by running the report repeatedly against a lab/QA server:
cd
do { .\bigipreport.ps1 } while { 0 -lt 1 }
Do note, that if you have a virtual lab edition, please make sure that you run it against the management interface and not one of the other types. Otherwise you might hit the throughput limit of 10mbit. 🙂
/Patrik