Sync-Failover Problems

I have had sporatic issues ever since upgrading to a new HA pair (4200) where after changes when you attempt to sync I will get an error that it could not complete. The only way I have ever been able to recover from this is to remove both hosts from the device group and peer list and set it all back up again. I am currently running BIG-IP 11.3.0 Build 3131.0 Hotfix HF6 but I had this issue on HF1 as well. Has anyone ever experienced this kind of issue?