Selecting Basque-end based on the SNI

If the F5 doesn't support the cryptography, you can't decrypt at the F5. And more importantly, you can't do SNI-based processing the easy way. Otherwise you could very easily build a CPM policy to load balance to different pools based on the SNI.

But since we're not talking about the easy way, I'll show you a harder way involving some layer 4 iRule parsing:

when CLIENT_ACCEPTED priority 300 {
    set detect_handshake 1
    TCP::collect
}
when CLIENT_DATA priority 200 {
    binary scan [TCP::payload] H* orig
    if { [binary scan [TCP::payload] cSS tls_xacttype tls_version tls_recordlen] < 3 } {
        reject
        return
    }

     768 SSLv3.0
     769 TLSv1.0
     770 TLSv1.1
     771 TLSv1.2
    switch $tls_version {
        "769" -
        "770" -
        "771" {
            if { ($tls_xacttype == 22) } {
                binary scan [TCP::payload] @5c tls_action
                if { not (($tls_action == 1) && ([TCP::payload length] > $tls_recordlen)) } {
                    set detect_handshake 0
                }
            }
        }
        "768" {
            set detect_handshake 0
        }
        default {
            set detect_handshake 0
        }
    }

    if { ($detect_handshake) } {
         skip past the session id
        set record_offset 43
        binary scan [TCP::payload] @${record_offset}c tls_sessidlen
        set record_offset [expr {$record_offset + 1 + $tls_sessidlen}]

         skip past the cipher list
        binary scan [TCP::payload] @${record_offset}S tls_ciphlen
        set record_offset [expr {$record_offset + 2 + $tls_ciphlen}]

         skip past the compression list
        binary scan [TCP::payload] @${record_offset}c tls_complen
        set record_offset [expr {$record_offset + 1 + $tls_complen}]

         check for the existence of ssl extensions
        if { ([TCP::payload length] > $record_offset) } {
             skip to the start of the first extension
            binary scan [TCP::payload] @${record_offset}S tls_extenlen
            set record_offset [expr {$record_offset + 2}]
             read all the extensions into a variable
            binary scan [TCP::payload] @${record_offset}a* tls_extensions

             for each extension
            for { set ext_offset 0 } { $ext_offset < $tls_extenlen } { incr ext_offset 4 } {
                binary scan $tls_extensions @${ext_offset}SS etype elen
                if { ($etype == 0) } {
                     if it's a servername extension read the servername
                    set grabstart [expr {$ext_offset + 9}]
                    set grabend [expr {$elen - 5}]
                    binary scan $tls_extensions @${grabstart}A${grabend} tls_servername_orig
                    set tls_servername [string tolower ${tls_servername_orig}]
                    set ext_offset [expr {$ext_offset + $elen}]
                    break
                } else {
                     skip over other extensions
                    set ext_offset [expr {$ext_offset + $elen}]
                }
            }
        }
    }

    if { ![info exists tls_servername] } {
         This isn't TLS so we can't decrypt it anyway
        SSL::disable clientside
        SSL::disable serverside
    } else {
        log local0. "tls_servername = ${tls_servername}"

         This is where you'd check a datagroup and disable SSL profiles as necessary


    }

    TCP::release
}

What you're looking at here is the standard iRule for SNI extraction at OSI layer 4 (TCP). At the end you see the clause that contains:

 This is where you'd check a datagroup and disable SSL profiles as necessary

This is where you have access the SNI in the ${tls_servername} variable, and where you could do your pool processing. You must also do this in a Standard VIP configuration to ensure client side TCP completes before starting server side TCP.