Remote access VPNS

if i understand you correctly then that is possible. the VPN end point is the virtual server with the APM network connect profile. the VPN users get their IPs from a local pool on the BIG-IP for which you can determine to which external interface the traffic is routed.

there are some hints here to doing this for multiple pools: https://devcentral.f5.com/questions/apm-portal-access-using-route-domains https://support.f5.com/kb/en-us/products/big-ip_apm/manuals/product/apm_config_10_1_0/apm_config_advanced_policies.html