Outlook Anywhere not working after the F5 Upgrade.

RPC over HTTP is not working on one of our F5 after upgrade, whereas it works on another one. It works fine for years using the old ip. While I am trying to connect to OA I am getting the following error message.

 

"Testing RPC over HTTP connectivity to server mail.domain.com RPC over HTTP connectivity failed"

 

Can anyone help me in this?