management api rest from tmm load-balanced traffic interfaces

Hello,

iControl REST is always "in-use" and enabled by default on the BIG-IP system. Please use below KB to find more details:

How to determine if a BIG-IP system is using iControl REST (f5.com)

If any self IPs are not accessible via API access, please check the port lockdown settings in interfaces. (port 443(https)/8443(rest API) need to be open in interfaces). For port lockdown understanding you can use below KBs:

Overview of port lockdown behavior (12.x - 17.x) (f5.com)