Load Balancing AWS Instances

I have installed my Big.IP in Vsphere Data Center and I have a Private subnet in AWS VPC which is connected to Vsphere through VPN tunnel. I have access to all instances running in the subnet from Bigip console i can able to ping. I am getting http response from that node. If I create node for those instances in bigip ant try to load balance. Health check is passing for all nodes but routing is not happening. Requests are not forwarded to the instances