lab LTM - networks not hitting default gateway

If I'm understanding correctly, your pool members aren't hitting their intended nodes. Ever since I ran into issues doing OCSP stapling I've become pretty aware of how the routing I have setup affects availability. One thing I've observed is that traffic on the Self-IPs do not use the default gateway of the mgmt interface, so I needed to add a route to a subnet, using the gateway of the network my internal interface is in.

Example:

Internal interface: 172.16.0.4/24 - gateway of 172.16.0.1

Target node IP: 172.16.1.4

Under network -> Routes, add a route

Destination: 172.16.1.0

Netmask: 255.255.255.0

Resource type: Gateway

Resource: 172.16.0.1

That's what I do; for things like OCSP, I lookup the IP of the OCSP responder with nslookup, and add /32 routes out to them. I might be being overly cautious by creating single IP routes to internet resources, that I need to 'host' locally, but I haven't found any major issues with it, and we aren't using it in a way where I want to integrate it with OSPF or BGP. I also want to avoid check and egg issues be I create a route to the network I have the mgmt interface on, but again, I might just be being overly cautious.