How to turn on Destination Address Affinity persistence

Destination Address Affinity Persistence:

 

 

 

Destination Address Affinity Persistence, also known as sticky persistance, directs requests for a certain destination IP address to the same server, regardless of which client made the request.

 

 

This type of persistence provides the most benefits when load balancing caching servers. A caching server intercepts web requests and returns a cached web page if it is available. In order to improve the efficiency of the cache on these servers, it is necessary to send similar request to same server repeatedly. You can use the destination address affinity persistence type to cache a given web page on one server instead of on every server in array. This saves the other servers from having to duplicate the web page in their cache, wasting memory.

 

 

 

I don't think your problem is going to be resolved by this. Recheck the VLAN configuration of your F5 and run a TCPDUMP on internal/external interfaces to see what's happening at packet level.