how to realized some clients persistence acording to source ip, but their src ip are not in one subnet?

Nice job, hoolio. Very creative use of univeral persistence.

If the match will always be on single IPs rather than subnet ranges, a slight refinement might offer better performance & scalability:

when CLIENT_ACCEPTED {
    check to see if client IP is in one of the datagroups
   set group [findclass [IP::client_addr] $::groups]
   if { $group != "" }{
       you can either specify the timeout value here or apply the iRule
       under a universal persistence profile and specify timeout there
      persist uie $group 500
   } else {
       client IP is not defined in any group, so take some default action
       or perhaps just use source address persistence?
   }
}

class groups {
   10.1.1.3 group1
   192.168.1.3 group1
   172.16.1.3 group1
   10.1.1.2 group2
   192.168.1.2 group2
   172.16.1.2 group2
   10.1.1.3 group3
   192.168.1.3 group3
   172.16.1.3 group3
}

Regardless of which version you use, you'll also either want to add a timeout to the "persist uie" command or be sure this rule is applied under a persistence profile of type "universal" to make sure stale persistence entries are reaped, otherwise you run the risk of memory exhuastion over time.

/deb