How to configure your node server web app to be use/show on the client side??

Aahh, ok, makes sense now. ;)

In order to do that, you first need to get a web server up and running on that Windows system, before you start putting it behind an F5 virtual server. Once the Windows server can show the website in a browser, will it be time to introduce the F5 VS.

Once you have a webserver running, have a look here: https://clouddocs.f5.com/training/community/adc/html/class1/class1.html - this is a basic lab for getting a load-balanced application to work through the F5. In the exercises they are talking about a different lab provider, but if you already have your systems setup, you can use your own.

Hope this helps.