F5 stream proxy support like nginx

I don't know nginx, but it looks like you have

a virtual server on port 8088 passing http with a reverse proxy and a pool member (app-foo-1) on port 8088

a virtual server on port 5223 that terminates TLS and then passes the decrypted data via stream to a pool member (stream_backend.foo) on port 5222.

a virtual server on port 5222 that passes connections to the pool member (stream_backend.foo) on port 5222.

All of this can be easily handled by an F5 LTM. Try the F5 free online training to see how ...