f5 reverse proxy to remove ports in URI

Client traffic comes on port :XXXXX already or is it HTTP(s) on standard port with the /vXX uri ? 
Do you backend server require the GET request to have the port specified? 

If you have only one virtual server, I'd configure two pools - one for port 42828 and one for port 9445 - and use a simple iRule (something like the following) to route traffic accordingly

when HTTP_REQUEST {
  if {[string tolower [HTTP::host]] ne "testws02.usneeded.com"}{ return }
  switch -regex [HTTP::uri] {
    ^\/v9\/   { pool p_testws02_9445 }
    ^\/v10\/  { pool p_testws02_42828 }
    default   { pool p_testws02_http }
  }
}

You could try using a local traffic policy:

create ltm policy Drafts/POLICY-REWRITE-TESTWS02.USNEEDED.COM strategy all-match rules add { v9 { ordinal 0 conditions add { 0 { http-host host equals values { testws02.usneeded.com } } 1 { http-uri path starts-with values { /v9 } } } actions add { 0 { http-uri replace value / } 1 { forward select node <NODE IP>:9445 } } } v10 { ordinal 1 conditions add { 0 { http-host host equals values { testws02.usneeded.com } } 1 { http-uri path starts-with values { /v10 } } } actions add { 0 { http-uri replace value / } 1 { forward select node <NODE IP>:42828 } } } }

publish ltm policy Drafts/POLICY-REWRITE-TESTWS02.USNEEDED.COM

modify ltm virtual <VS NAME> policies add { POLICY-REWRITE-TESTWS02.USNEEDED.COM }