F5 Big-IP Edge client proxy issue

All our users must use proxy. In order for Edge client to work we've added our F5 APM address (apm.mydomain.com) to IE exclusion list. (We are not using option for Client Proxy Settings in network access list) Now Edge client is able to reach APM and establish SSL connection. The moment Edge client kicks in it takes over proxy management in IE by removing tick for original "Use proxy server..." and instead ticks the box "Use automatic configuration script" and point browser to Temp folder location where autogenerated script is located. Script file contains all the deatils from our IE exclusion list. What happens now is F5 Edge client proxy engine should take controll over requests but it doesn't. Web broser IE would become unresponsive and web browsing is not possible.