F5 APM for Windows Server HTML5 RDP client with MFA

I have been able to use a combination of an iApp for RDP Gateway to set up APM with SSO and MFA for a native Windows Server RDP client. 

Is it possible to do all/some of the same things for the HTML5 Windows Server Client?  I have looked at the F5 and RemoteSpark solution, but I was hoping to cobble something together that didn't use RemoteSpark?

I welcome any and all suggestions.