Exclude application request logging for single uri

Well (Security ›› Event Logs : Application : Requests GUI) thats one way to do. Other way is to tweak you Irule logging method itself.

Can you give us a glimpse of your existing irule and how you are logging them. Since you say you want to exclude a particular URI alone. Why not set that in a variable first.

Do a if condition and skip logging if it matches.