Exchange OWA ActiveSync Outlook Anywhere with F5

Exchange is, unfortunately, a very complex application, so you'll need to pour a cup (or 10) of coffee and consume as much as you can about the deployment options. Thankfully the Exchange iApp goes A LONG WAY towards simplifying that process as possible. The document you reference is the guide that talks about what the iApp is doing and what is required to use it. Actual iApp execution is surprisingly very fast. It'll create multiple VIPs on different ports for OWA, OA, auto discovery, and optionally ActiveSync. I highly recommend this approach.