Enable and Apply Server SSL Profile through iRule

you have to assign serverssl profile to the virtual server and disable/enable it in irule.

e.g.

when HTTP_REQUEST {
  SSL::disable serverside
  switch -glob [HTTP::uri] {
    "/AAA" { pool AAAServers_http } 
    "/BBB" { pool BBBServers_http } 
    "/CCC" { pool CCCServers_http } 
    "/DDD" { 
      SSL::enable serverside
      pool DDDServers_https 
    } 
  }
}