DVWA site is very slow when datasafe profile applied

Seçkin - no assistance yet from the community?
Have you reviewed this set of pages in TechDocs - https://techdocs.f5.com/en-us/bigip-15-1-0/fraud-protection-service-big-ip-configuration/creating-an-initial-big-ip-datasafe-profile.html

I don't see anything referencing performance in there but I also see this supplemental doc which lists a known issue in the GUI (maybe off topic but...worth a look)

https://techdocs.f5.com/kb/en-us/products/big-ip_ltm/releasenotes/related/relnote-supplement-bigip-15-1-5.html

If this doesn't help let me know and I'll see if I can get a proper SME on this thread. 😄