Chrome 80 and http/2 profile

Edit: actually, you indicate the issue is seen on 12.1.4, so this probably isn't the issue. Opening a case and providing a qkview and details of the issue will help us narrow the potential cause.

Thanks, Aaron

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This might be the issue you're seeing. It would be great if you can open a support case and provide more exact details on the version and issue.

Bug ID 677119: HTTP2 implementation incorrectly treats SETTINGS_MAX_HEADER_LIST_SIZE

https://cdn.f5.com/product/bugtracker/ID677119.html

Symptoms

When HTTP2 connection's parameters are negotiated, either side may report about its limits in SETTINGS type frame where one of the parameters SETTINGS_MAX_HEADER_LIST_SIZE determines a maximum size of headers list it is willing to accept. The BIG-IP system incorrectly interchanged this parameter with another one called SETTINGS_HEADER_TABLE_SIZE, limiting value of the former one to 32,768.

Fixed In:

13.0.1, 12.1.3, 11.6.3.2

Aaron