ASM::disable doesn't work

I don't think you need the "if {[HTTP::class asm]==1}{" statement as you are selecting the disabling against the disable_asm string being a value of 1 so the second if statement doesn't appear to be required.

We do the same thing but we don't use a datagroup for the URI list but just encode the lines directly into the iRule for the application and all under the HTTP_CLASS_SELECTED method. Example of the different ways we do this below.

when HTTP_CLASS_SELECTED {

if { [IP::addr [IP::client_addr]/32 equals 10.x.x.x] } {
         ASM::disable
         return
   } elseif  { [IP::addr [IP::client_addr]/26 equals 10.x.x.x] } {
         ASM::disable
         return
   } else {
       ASM::enable
   }


if { [HTTP::header "User-Agent"] contains "Mozilla" }  {
        ASM::disable
    return 
}

set test_uri [string tolower [HTTP::uri]]

    if { $test_uri contains "/rpc" } {
           ASM::disable
           return
    } elseif { $test_uri contains "/owa" } {
           ASM::disable
           return
    } elseif { $test_uri contains "/microsoft-server-activesync" } {
           ASM::disable
           return   
    } elseif { $test_uri contains "/ucm/cma/" } {
           ASM::disable
           return   
    } elseif { $test_uri contains "/preview.aspx" } {
           ASM::disable
           return      
        } else {
           ASM::enable
    }

   switch -glob $test_uri {
      "*.css" { set test_uri [string map {.css "" } $test_uri]  }
      "*.gif" { set test_uri [string map {.gif "" } $test_uri]  }
      "*.ico" { set test_uri [string map {.ico "" } $test_uri]  }
      "*.jpg" { set test_uri [string map {.jpg "" } $test_uri]  }
      "*.bmp" { set test_uri [string map {.bmp "" } $test_uri]  }
      "*.doc" { set test_uri [string map {.doc "" } $test_uri]  }
      "*.docx" { set test_uri [string map {.docx "" } $test_uri]  }
      "*.dot" { set test_uri [string map {.dot "" } $test_uri]  }
      "*.ico" { set test_uri [string map {.ico "" } $test_uri]  }
      "*.mp3" { set test_uri [string map {.mp3 "" } $test_uri]  }
      "*.pdf" { set test_uri [string map {.pdf "" } $test_uri]  }
      "*.png" { set test_uri [string map {.png "" } $test_uri]  }
      "*.pps" { set test_uri [string map {.pps "" } $test_uri]  }
      "*.ppsx" { set test_uri [string map {.ppsx "" } $test_uri]  }
      "*.ppt" { set test_uri [string map {.ppt "" } $test_uri]  }
      "*.pptx" { set test_uri [string map {.pptx "" } $test_uri]  }
      "*.swf" { set test_uri [string map {.swf "" } $test_uri]  }
      "*.vsd" { set test_uri [string map {.vsd "" } $test_uri]  }
      "*.wav" { set test_uri [string map {.wav "" } $test_uri]  }
      "*.wma" { set test_uri [string map {.wma "" } $test_uri]  }
      "*.xls" { set test_uri [string map {.xls "" } $test_uri]  }
      "*.xlsx" { set test_uri [string map {.xlsx "" } $test_uri]  }
      "*.zip" { set test_uri [string map {.zip "" } $test_uri]  }
      default {
      return
      }
   }

 Verify method is GET

   if {not ([HTTP::method] eq "GET")}{
      return
   }
   if { ([HTTP::method] eq "POST")}{
      ASM::disable
      return
   }
}