2 Locations - 4 LTMs, 2 GTM licenses - redundant setup question

Hello,

 

 

We have the following

 

 

Location A

 

2 LTMs with 1 having a GTM module license

 

 

Location B

 

2 LTMs with 1 having a GTM module license

 

 

In each location we want to configure the LTMs to be in a redundant cluster. Can the two GTMs be configured as a seperate redundant cluster running between the two sites? Is that possible?