Just upgraded LTMs from version 18.104.22.168.0.378 to 22.214.171.124 Build 0.0.10 Point Release 2.
Have VSs that request Client Authentication, and an iRule that loops through the client certs, and scrutinizes the certificates.
The Point Release delivers the client certificates in a different format than version 126.96.36.199.0. This caused the iRule to reject the certificates.
So if you have a VS that request and examines client certificates, and are going to install a version that fixes CVE 2020-5902, please be aware that you may have to edit you iRule to look for a slightly different format.