Window 1903 user are facing an issue on APM

you might want to change that to Windows 10 1903 to make it more clear.

i don't see anyone else mention this and 1903 was released in may 2019 so i doubt it is a general issue between Windows 10 and F5 APM.

which TMOS version are you using? are you using browser or Edge client? do you do any client status checking? what error do you get?

if this is important then you should consider opening a support ticket with F5.