What configuration issue am I experiencing with this 130-domain VS ?

Hello, I am using an F5 WAF device running BIG-IP ISO version 16.1.4.2. I am currently facing an issue within a Virtual Server (VS) that runs a total of 130 domains. When the F5 WAF device undergoes CPU overload, only the services hosted on this specific 130-domain VS are failing, while all other Virtual Servers continue to operate normally. What configuration issue am I experiencing with this 130-domain VS, and what is the resolution for it? For the time being, I have disabled this VS to keep the F5 WAF device running stably. Thank you very much!