Replacing hostname in HTTP RESPONSE header using stream profile and/or Irule

Hello , Was there ever a solution for this? We are currently trying to mask an public domain (i.e. "support.com") between browser and the f5, but serve content from the back-end server with "myqadcloud.com" (from f5 to back-end server); and finally on each response from back-end server should ensure all domains used are "support.com" domain. Long story short, in theory, this method would prevent cross domain errors from IFrames within parent windows that contains a different domain name. So in a sense we are fooling the browser that the parent and iframe domain are the same, but the iframe will server content from a different back-end server (myqadcloud.com).

Thoughts on how that can be done?

Thanks in advance.

Traolly Xiong