On-prem Exchange ingration with O365 using F5 LTM

Does anyone have any documented solution integrating On-prem exchange environment through Exchange CAS services to O365. Looking at a hybrid solution here utilizing F5 LTM only as ADFS is been used to federate to O365. Interested to understand the flows i.e. mailbox migration and also traffic hybrid flow outbound to O365 and inbound flow from O365.

Is this the case of making use of iApp and SMTP standard virtual server for inbound flow and outbound flow using an IP forwarding Virtual Server.

Any advice much appreciated.