Noob: Website is not available.

Alrighty, first thing first, need to clarify the situation:

So, we have some F5 gear, is it just LTM (load balancing) or AFM (Firewall)?

Next, the network:

External/Client IPs: (looks like you call them Untrust IPs?) 6.6.6.41

Virtual Server IPs: 6.6.6.42 - Direct to Webserver.. do you mean it goes around the F5 device? Or is it a fastl4 virtual server? 6.6.6.44 - Says Mays to Prod IP 1.1.1.142, Do you mean this virtual server has a pool assigned to it, that contains the pool member 1.1.1.142?

Pool Members: 1.1.1.142:80 ?

So... Quick DL on a basic Load Balanced HTTP server Setup.

3 Components: Clients Virtual Server Pool

------Clients: Where your traffic sources from, say IP: X.X

------Virtual Server: Listener on the LTM that is listening for connections from the Clients. In the case of an HTTP setup, we'd have something like:

IP: y.y.y.y Port: 80 Snat: Automap (often needed to clear up asymmetric routing issues. Can explain more, but that's another conversation) Http Profile: HTTP

-----Pool: Contains the IPs of the actual webservers and the port they are listening on. In case of basic HTTP:

IP:z.z.z.z PORT: 80 Monitor: HTTP (checks to be sure the member can be reached by the F5.

So the traffic path looks like:

Client X.X -----> LTM VS Y.Y.Y.Y:80 ---> POOL Member z.z.z.z:80