FTP and HTTP on same virtual server

Is there any way to disable compression in the web server, via configuration? You could try that first, then let your LTM do compression.

Another way is to fool your webserver into *not* compressing content by stripping out the Accept-Encoding headers sent by the client with an iRule. Your server would send back uncompressed text, which you'd be free to manipulate (and then compress in hardware). You could do that in a rule as simple as this:

    
 when HTTP_REQUEST {    
    if { [HTTP::header exists "Accept-Encoding"] } {    
       HTTP::header remove "Accept-Encoding"    
    }    
 }