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Migrated from various hardware > 10200v and changed VLAN
Best practice, assuming a single traffic group, would be one self IP per VLAN per ltm instance (if two instances in HA pair, one self IP for each per VLAN) and one floating IP per HA setup per VLAN. So if you have 3 devices, in actice-active-standby for example, you would have 4 IPs used; 3 self IPs and one floating IP, again per VLAN.
As for when you add them. I would definitely do this after hours. I'm not 100% certain, but I think if you add the self/floating IPs on a VLAN that has nodes then the F5 would starting sending traffic via that floating IP so application traffic would go to your servers from a different IP. If you are dealing with firewalls in between the F5 and the client/destination you'll also need to make sure that the firewall rules are updated. Hope this helps.
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